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primary monoclonal mouse trpc1 antibody  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology primary monoclonal mouse trpc1 antibody
    Immunohistochemistry (IHC) staining of breast tumor and neighboring normal breast tissue. ( A ) Representative IHC images showing <t>TRPC1</t> and Ki-67 staining (brown) in breast tumor (Grade 1 and 3) and neighboring normal breast tissue. Tissue sections were counterstained with hematoxylin (blue). The scale bar is 50 μm. ( B ) Semi-quantitative IHC analysis of TRPC1 and Ki-67 staining intensity. Staining intensity was scored as: 0 (no staining), 1 (weak), 2 (moderate) or 3 (strong staining). Data represent mean ± standard error of the mean (SEM). The number of independent samples is reflected within each bar, and the samples were analyzed using one-way ANOVA, followed by Šidák’s multiple comparison post hoc test. Statistical significance is indicated by **, p ≤ 0.01 and ***, p ≤ 0.001.
    Primary Monoclonal Mouse Trpc1 Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 185 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary monoclonal mouse trpc1 antibody/product/Santa Cruz Biotechnology
    Average 94 stars, based on 185 article reviews
    primary monoclonal mouse trpc1 antibody - by Bioz Stars, 2026-02
    94/100 stars

    Images

    1) Product Images from "Brief Magnetic Field Exposure Stimulates Doxorubicin Uptake into Breast Cancer Cells in Association with TRPC1 Expression: A Precision Oncology Methodology to Enhance Chemotherapeutic Outcome"

    Article Title: Brief Magnetic Field Exposure Stimulates Doxorubicin Uptake into Breast Cancer Cells in Association with TRPC1 Expression: A Precision Oncology Methodology to Enhance Chemotherapeutic Outcome

    Journal: Cancers

    doi: 10.3390/cancers16223860

    Immunohistochemistry (IHC) staining of breast tumor and neighboring normal breast tissue. ( A ) Representative IHC images showing TRPC1 and Ki-67 staining (brown) in breast tumor (Grade 1 and 3) and neighboring normal breast tissue. Tissue sections were counterstained with hematoxylin (blue). The scale bar is 50 μm. ( B ) Semi-quantitative IHC analysis of TRPC1 and Ki-67 staining intensity. Staining intensity was scored as: 0 (no staining), 1 (weak), 2 (moderate) or 3 (strong staining). Data represent mean ± standard error of the mean (SEM). The number of independent samples is reflected within each bar, and the samples were analyzed using one-way ANOVA, followed by Šidák’s multiple comparison post hoc test. Statistical significance is indicated by **, p ≤ 0.01 and ***, p ≤ 0.001.
    Figure Legend Snippet: Immunohistochemistry (IHC) staining of breast tumor and neighboring normal breast tissue. ( A ) Representative IHC images showing TRPC1 and Ki-67 staining (brown) in breast tumor (Grade 1 and 3) and neighboring normal breast tissue. Tissue sections were counterstained with hematoxylin (blue). The scale bar is 50 μm. ( B ) Semi-quantitative IHC analysis of TRPC1 and Ki-67 staining intensity. Staining intensity was scored as: 0 (no staining), 1 (weak), 2 (moderate) or 3 (strong staining). Data represent mean ± standard error of the mean (SEM). The number of independent samples is reflected within each bar, and the samples were analyzed using one-way ANOVA, followed by Šidák’s multiple comparison post hoc test. Statistical significance is indicated by **, p ≤ 0.01 and ***, p ≤ 0.001.

    Techniques Used: Immunohistochemistry, Staining, Comparison

    Magnetic field-induced DOX uptake correlates with TRPC1 expression. ( A ) Bar chart showing the fold change in intracellular DOX concentration of 4T1 cells pre-treated with 50 µM SKF-96365 for 15 min and 500 nM DOX for 5 min prior to 10 min magnetic exposure (n = 4). ( B ) Bar chart showing fold changes in TRPC1 transcript levels as detected by qPCR in 4T1 cells transfected with scrambled or TRPC1 dsiRNA after 24 h. Data represent mean ± standard deviation, (n = 3 technical replicates). ( C ) Bar chart showing fold change in intracellular DOX concentration in 4T1 cells transfected with scramble or TRPC1 dsiRNA. Cells were pre-treated with 500 nM DOX for 5 min prior to 10 min magnetic exposure (n = 3). ( D ) Bar chart showing fold change in TRPC1 transcript level detected by qPCR in MCF7 and MCF7 stable cell line overexpressing TRPC1 (MCF7-TRPC1) cells (n = 3). ( E ) Western blot of GFP-TRPC1 in MCF7 and MCF7-TRPC1 cells (n = 4). The uncropped blots are shown in . ( F ) Bar chart showing the fold change in intracellular DOX concentration of MCF7 and MCF7-TRPC1 cells pre-treated with 500 nM DOX for 5 min prior to 10 min of magnetic exposure (n = 4). Unless otherwise stated, data represent mean ± standard error of the mean (SEM). Statistical analysis was performed using one-way ANOVA, followed by Šidák’s multiple comparison post hoc test. Significance is indicated by ns (not significant); **, p ≤ 0.01; ***, p ≤ 0.001; and ****, p ≤ 0.0001.
    Figure Legend Snippet: Magnetic field-induced DOX uptake correlates with TRPC1 expression. ( A ) Bar chart showing the fold change in intracellular DOX concentration of 4T1 cells pre-treated with 50 µM SKF-96365 for 15 min and 500 nM DOX for 5 min prior to 10 min magnetic exposure (n = 4). ( B ) Bar chart showing fold changes in TRPC1 transcript levels as detected by qPCR in 4T1 cells transfected with scrambled or TRPC1 dsiRNA after 24 h. Data represent mean ± standard deviation, (n = 3 technical replicates). ( C ) Bar chart showing fold change in intracellular DOX concentration in 4T1 cells transfected with scramble or TRPC1 dsiRNA. Cells were pre-treated with 500 nM DOX for 5 min prior to 10 min magnetic exposure (n = 3). ( D ) Bar chart showing fold change in TRPC1 transcript level detected by qPCR in MCF7 and MCF7 stable cell line overexpressing TRPC1 (MCF7-TRPC1) cells (n = 3). ( E ) Western blot of GFP-TRPC1 in MCF7 and MCF7-TRPC1 cells (n = 4). The uncropped blots are shown in . ( F ) Bar chart showing the fold change in intracellular DOX concentration of MCF7 and MCF7-TRPC1 cells pre-treated with 500 nM DOX for 5 min prior to 10 min of magnetic exposure (n = 4). Unless otherwise stated, data represent mean ± standard error of the mean (SEM). Statistical analysis was performed using one-way ANOVA, followed by Šidák’s multiple comparison post hoc test. Significance is indicated by ns (not significant); **, p ≤ 0.01; ***, p ≤ 0.001; and ****, p ≤ 0.0001.

    Techniques Used: Expressing, Concentration Assay, Transfection, Standard Deviation, Stable Transfection, Western Blot, Comparison



    Similar Products

    primary monoclonal mouse trpc1 antibody  (Santa Cruz Biotechnology)
    94
    Santa Cruz Biotechnology primary monoclonal mouse trpc1 antibody
    Immunohistochemistry (IHC) staining of breast tumor and neighboring normal breast tissue. ( A ) Representative IHC images showing <t>TRPC1</t> and Ki-67 staining (brown) in breast tumor (Grade 1 and 3) and neighboring normal breast tissue. Tissue sections were counterstained with hematoxylin (blue). The scale bar is 50 μm. ( B ) Semi-quantitative IHC analysis of TRPC1 and Ki-67 staining intensity. Staining intensity was scored as: 0 (no staining), 1 (weak), 2 (moderate) or 3 (strong staining). Data represent mean ± standard error of the mean (SEM). The number of independent samples is reflected within each bar, and the samples were analyzed using one-way ANOVA, followed by Šidák’s multiple comparison post hoc test. Statistical significance is indicated by **, p ≤ 0.01 and ***, p ≤ 0.001.
    Primary Monoclonal Mouse Trpc1 Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary monoclonal mouse trpc1 antibody/product/Santa Cruz Biotechnology
    Average 94 stars, based on 1 article reviews
    primary monoclonal mouse trpc1 antibody - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    Immunohistochemistry (IHC) staining of breast tumor and neighboring normal breast tissue. ( A ) Representative IHC images showing TRPC1 and Ki-67 staining (brown) in breast tumor (Grade 1 and 3) and neighboring normal breast tissue. Tissue sections were counterstained with hematoxylin (blue). The scale bar is 50 μm. ( B ) Semi-quantitative IHC analysis of TRPC1 and Ki-67 staining intensity. Staining intensity was scored as: 0 (no staining), 1 (weak), 2 (moderate) or 3 (strong staining). Data represent mean ± standard error of the mean (SEM). The number of independent samples is reflected within each bar, and the samples were analyzed using one-way ANOVA, followed by Šidák’s multiple comparison post hoc test. Statistical significance is indicated by **, p ≤ 0.01 and ***, p ≤ 0.001.

    Journal: Cancers

    Article Title: Brief Magnetic Field Exposure Stimulates Doxorubicin Uptake into Breast Cancer Cells in Association with TRPC1 Expression: A Precision Oncology Methodology to Enhance Chemotherapeutic Outcome

    doi: 10.3390/cancers16223860

    Figure Lengend Snippet: Immunohistochemistry (IHC) staining of breast tumor and neighboring normal breast tissue. ( A ) Representative IHC images showing TRPC1 and Ki-67 staining (brown) in breast tumor (Grade 1 and 3) and neighboring normal breast tissue. Tissue sections were counterstained with hematoxylin (blue). The scale bar is 50 μm. ( B ) Semi-quantitative IHC analysis of TRPC1 and Ki-67 staining intensity. Staining intensity was scored as: 0 (no staining), 1 (weak), 2 (moderate) or 3 (strong staining). Data represent mean ± standard error of the mean (SEM). The number of independent samples is reflected within each bar, and the samples were analyzed using one-way ANOVA, followed by Šidák’s multiple comparison post hoc test. Statistical significance is indicated by **, p ≤ 0.01 and ***, p ≤ 0.001.

    Article Snippet: Primary monoclonal mouse TRPC1 antibody (E-6) (1:50; catalogue no.: sc-133076; Santa Cruz Biotechnology, Dallas, TX, USA) and monoclonal rabbit antigen Kiel 67 (Ki-67) antibody (1:400; catalogue no.: #9129; Cell Signaling Technologies, Danvers, MA, USA) were used.

    Techniques: Immunohistochemistry, Staining, Comparison

    Magnetic field-induced DOX uptake correlates with TRPC1 expression. ( A ) Bar chart showing the fold change in intracellular DOX concentration of 4T1 cells pre-treated with 50 µM SKF-96365 for 15 min and 500 nM DOX for 5 min prior to 10 min magnetic exposure (n = 4). ( B ) Bar chart showing fold changes in TRPC1 transcript levels as detected by qPCR in 4T1 cells transfected with scrambled or TRPC1 dsiRNA after 24 h. Data represent mean ± standard deviation, (n = 3 technical replicates). ( C ) Bar chart showing fold change in intracellular DOX concentration in 4T1 cells transfected with scramble or TRPC1 dsiRNA. Cells were pre-treated with 500 nM DOX for 5 min prior to 10 min magnetic exposure (n = 3). ( D ) Bar chart showing fold change in TRPC1 transcript level detected by qPCR in MCF7 and MCF7 stable cell line overexpressing TRPC1 (MCF7-TRPC1) cells (n = 3). ( E ) Western blot of GFP-TRPC1 in MCF7 and MCF7-TRPC1 cells (n = 4). The uncropped blots are shown in . ( F ) Bar chart showing the fold change in intracellular DOX concentration of MCF7 and MCF7-TRPC1 cells pre-treated with 500 nM DOX for 5 min prior to 10 min of magnetic exposure (n = 4). Unless otherwise stated, data represent mean ± standard error of the mean (SEM). Statistical analysis was performed using one-way ANOVA, followed by Šidák’s multiple comparison post hoc test. Significance is indicated by ns (not significant); **, p ≤ 0.01; ***, p ≤ 0.001; and ****, p ≤ 0.0001.

    Journal: Cancers

    Article Title: Brief Magnetic Field Exposure Stimulates Doxorubicin Uptake into Breast Cancer Cells in Association with TRPC1 Expression: A Precision Oncology Methodology to Enhance Chemotherapeutic Outcome

    doi: 10.3390/cancers16223860

    Figure Lengend Snippet: Magnetic field-induced DOX uptake correlates with TRPC1 expression. ( A ) Bar chart showing the fold change in intracellular DOX concentration of 4T1 cells pre-treated with 50 µM SKF-96365 for 15 min and 500 nM DOX for 5 min prior to 10 min magnetic exposure (n = 4). ( B ) Bar chart showing fold changes in TRPC1 transcript levels as detected by qPCR in 4T1 cells transfected with scrambled or TRPC1 dsiRNA after 24 h. Data represent mean ± standard deviation, (n = 3 technical replicates). ( C ) Bar chart showing fold change in intracellular DOX concentration in 4T1 cells transfected with scramble or TRPC1 dsiRNA. Cells were pre-treated with 500 nM DOX for 5 min prior to 10 min magnetic exposure (n = 3). ( D ) Bar chart showing fold change in TRPC1 transcript level detected by qPCR in MCF7 and MCF7 stable cell line overexpressing TRPC1 (MCF7-TRPC1) cells (n = 3). ( E ) Western blot of GFP-TRPC1 in MCF7 and MCF7-TRPC1 cells (n = 4). The uncropped blots are shown in . ( F ) Bar chart showing the fold change in intracellular DOX concentration of MCF7 and MCF7-TRPC1 cells pre-treated with 500 nM DOX for 5 min prior to 10 min of magnetic exposure (n = 4). Unless otherwise stated, data represent mean ± standard error of the mean (SEM). Statistical analysis was performed using one-way ANOVA, followed by Šidák’s multiple comparison post hoc test. Significance is indicated by ns (not significant); **, p ≤ 0.01; ***, p ≤ 0.001; and ****, p ≤ 0.0001.

    Article Snippet: Primary monoclonal mouse TRPC1 antibody (E-6) (1:50; catalogue no.: sc-133076; Santa Cruz Biotechnology, Dallas, TX, USA) and monoclonal rabbit antigen Kiel 67 (Ki-67) antibody (1:400; catalogue no.: #9129; Cell Signaling Technologies, Danvers, MA, USA) were used.

    Techniques: Expressing, Concentration Assay, Transfection, Standard Deviation, Stable Transfection, Western Blot, Comparison